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Source: COVID-19 Supplements  Aug 11, 2020  3 years, 8 months, 6 days, 22 hours, 27 minutes ago

COVID-19 Supplements: Be Careful When Buying Vitamin D Supplements As There Are Many Forms - Cholecalciferol (D3), Ergocalciferol(D2), Calcifediol, And Calcitriol

COVID-19 Supplements: Be Careful When Buying Vitamin D Supplements As There Are Many Forms - Cholecalciferol (D3), Ergocalciferol(D2), Calcifediol, And Calcitriol
Source: COVID-19 Supplements  Aug 11, 2020  3 years, 8 months, 6 days, 22 hours, 27 minutes ago
COVID-19 Supplements: If you thought that buying supplements was easy, think again. As a result of greed and profitability, many manufacturers especially those in Asia will find ways to put in the cheapest ingredient or form and not really focus on the true effectiveness of the product and whether it will truly help the end consumers.


 
The media has been abuzz recently about the proven benefits of Vitamin D in helping certain aspects of managing the COVID-19 disease but procuring the right product has proven to be a more difficult task and many are simply taking supplements that might not really help them due to lax labeling laws and regulatory measures.
 
When it comes to Vitamin D, most people should first understand that current labeling laws allow any four existing forms of compounds be labeled as Vitamin D Supplements.
 
It has been found that the specific compound that is meant for use in the context of vitamin D supplementation is often ambiguous. The term “supplementation” has been used in the context of cholecalciferol, ergocalciferol, calcidiol, and calcitriol. https://www.nature.com/articles/s41430-020-0697-1
 
The only naturally occurring form of Vitamin D that nurtures the body is cholecalciferol or Vitamin D3. It is produced by the human body in response to sunlight and is also available through dietary sources, such as fish but it is also an expensive product for use in supplements.
 
However a much cheaper version is ergocalciferol ior Vitaminb D2 and is primarily a synthetic and less stable product which is less potent per microgram dose than is cholecalciferol. This is the product that is frequently passed off as Vitamin D by most supplement companies.
 
The compound Calcidol is the major circulating metabolite of cholecalciferol, while Calcitriol is the hormone that upregulates the active transport of calcium from the gut, and which suppresses parathyroid hormone secretion.
 
Typically, nutrition policy papers and guidelines leave unstated the obvious fact that calcidiol and calcitriol are not nutrients, and that those metabolites are not pertinent to food fortification or dietary supplementation. There is however synthetic forms of calcidiol and calcitriol available cheaply and in some countries with clueless regulatory authorities and lax laws, they are sometimes passed off as Vitamin D.  China is one of the few countries that is able to supply these cheaper synthetic forms at extremely cheap rates and their customers includes supplement manufacturing companies in the US and most South-East Asian countries.
 
Numerous recent studies show that ergocalciferol is not stable with storage, and it is far more susceptible to breakdown with co