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Source: COVID-19-Eyes  Nov 01, 2021  2 years, 5 months, 2 weeks, 2 days, 21 hours, 34 minutes ago

Spanish Study Finds That SARS-CoV-2 Coronavirus Present in Tears And Ocular Secretions of Individuals With COVID-19

Spanish Study Finds That SARS-CoV-2 Coronavirus Present in Tears And Ocular Secretions of Individuals With COVID-19
Source: COVID-19-Eyes  Nov 01, 2021  2 years, 5 months, 2 weeks, 2 days, 21 hours, 34 minutes ago
COVID-19-Eyes: A study by researchers from University of Santiago de Compostela-Spain and the University Hospital of Santiago de Compostel-Spain has found that the infectious form of the SARS-CoV-2 virus is present in the tears and ocular secretions of individuals with COVID-19.

 
The study team investigated the presence of SARS-CoV-2 in conjunctival secretions and tears and evaluated ocular symptoms in a group of patients with COVID-19.
 
The cross-sectional cohort study included 56 hospitalized patients with COVID-19. Conjunctival secretions and tears were collected using flocked swabs and Schirmer strips for SARS-CoV-2 reverse-transcriptase polymerase chain reaction (RT-PCR). Assessment of ocular surface manifestations included an OSDI (Ocular Surface Disease Index) questionnaire. Patients had been admitted to hospital for an average of 2.4 days (range 0–7) and had shown general symptoms for an average of 7.1 days (range 1–20) prior to ocular testing. Four (7.1%) of 56 conjunctival swabs and four (4%) of 112 Schirmer strips were positive for SARS-CoV-2. The mean E-gene cycle threshold values (Ct values) were 31.2 (SD 5.0) in conjunctival swabs and 32.9 (SD 2.7) in left eye Schirmer strips. Overall, 17 (30%) patients presented ocular symptoms. No association was found between positive ocular samples and ocular symptoms.
 
The study findings shos that SARS-CoV-2 can be detected on the conjunctiva and tears of patients with COVID-19. Contact with the ocular surface may transmit the virus and preventive measures should be taken in this direction.
 
The study findings were published in the peer reviewed journal: Vision. https://www.mdpi.com/2411-5150/5/4/51/htm
 
To date it has been known that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is present in respiratory droplets. Transmission of SARS-CoV-2 through droplets can infect individuals, thus causing coronavirus disease 2019 (COVID-19).
 
This new study investigates the presence of SARS-CoV-2 in tears and eye secretions and describes the ocular symptoms in patients with COVID-19.

Typically, patients with COVID-19 often present with fever, cough, shortness of breath, muscle weakness and pain, as well as various gastrointestinal symptoms. Patients with severe COVID-19 may also develop bilateral pneumonia and hypoxemia. When severe COVID-19 leads to cytokine storms, multiple organs can get affected.
 
The SARS-CoV-2 has been detected in tears and conjunctival secretions, mostly in patients hospitalized with severe COVID-19. These patients also demonstrate ocular manifestations of the disease.
 
This cross-sectional cohort study involving 56 hospitalized patients, was a single-site study conducted at the University Hospital of Santiago de Compostela in Spain.
 
The participants were eligible to participate in the current study if they had reverse-transcriptase polymerase chain reaction (RT-PCR)-confirmed SARS-CoV-2 infection from a nasopharyngeal swab and were within the first 20 days from the onset of sym