BREAKING! Physicians At University of California-San Diego Report About Young Healthy COVID-19 Patient Developing CNS Lymphocytic Vasculitis!
COVID-19 Clinical Care
: Researchers and physicians from the University of California-San Diego Health (A trauma hospital) report the clinical manifestation of a young and previously healthy COVID-19 patient developing
CNS Lymphocytic Vasculitis.
Central nervous system (CNS) vasculitis typically means that blood vessel walls in the brain and spine are inflamed (swollen).
The clinical report was published on the July 28, 2021 in the journal Neurology: Neuroimmunology & Neuroinflammation
While COVID-19 is primarily treated as a respiratory disease, patients often experience neurological problems, such as headaches, anxiety, depression and cognitive issues, which can persist long after other symptoms have resolved.
Certain research has shown blood vessel damage and inflammation referred to as vasculitis in COVID-19 patients' brains and central nervous system (CNS).
However most cases of CNS vasculitis have been typically associated with elderly patients with severe COVID-19. https://jnnp.bmj.com/content/92/1/103.abstract
In this alarming development, a multidisciplinary team of physicians at University of California San Diego School of Medicine describe the first known case of a young, healthy adult infected by the SARS-CoV-2 virus who also experienced CNS lymphocytic vasculitis
Dr Jennifer Graves, MD, PhD, is a neurologist at UC San Diego Health.
The 26-year-old woman was diagnosed with COVID-19 four days after an airplane flight in mid-March 2020. Her symptoms were mild, but progressed two to three weeks later to difficulty moving her left foot and weakness on the left side of her body. She had no headaches and had experienced no change in her mental status or cognition.
MRI or magnetic resonance imaging, however, revealed multiple lesions in the right frontoparietal region of the brain, which is involved in motor control and sensation of the left side of the body.
A biopsy revealed CNS lymphocytic vasculitis ie inflammation or swelling of blood vessels in the brain and spine.
The female COVID-19 patient underwent a series of corticosteroid-based treatments, began a long-term immunosuppressive medication, and, after six months, the lesions had substantially decreased and no new lesions had formed.
The patient is still under treatment with immunosuppressive medication
From a documented clinical perspective, this patient was first confirmed case of COVID-19 CNS vasculitis, confirmed by biopsy, in a young healthy patient with otherwise mild COVID-19 infection.
The female COVID-19 patient case tells researchers and clinicians to consider these serious potential brain complications even in young patients and those with minor initial COVID-19 infections."
Dr Jennifer Graves, MD, PhD was the corresponding senior author and besides being a neurologist at University of California-San Diego Health is an associate professor of neurosciences at UC San Diego School of Medicine.
It should be noted that CNS vasculitis is a serious condition. The inflamed vessel wall can block the flow of oxygen to the brain, causing a loss of brain function and ultimately strokes. In some cases, CNS vasculitis is life-threatening. It’s important to get rapid diagnosis and treatment for this condition.
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