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Source: COVID Rehab  Aug 04, 2020  3 years, 8 months, 1 week, 2 days, 23 hours, 19 minutes ago

COVID-19 Rehab: Supplements That Could Help With Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis Manifesting In ‘Recovered’ COVID-19 Patients

COVID-19 Rehab: Supplements That Could Help With Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis Manifesting In ‘Recovered’ COVID-19 Patients
Source: COVID Rehab  Aug 04, 2020  3 years, 8 months, 1 week, 2 days, 23 hours, 19 minutes ago
COVID-19 Rehab: With official figures showing that almost 18.5 million individuals infected with the COVID-19 disease and tens of millions more asymptomatic individuals and infected people who have yet to be tested, the medical and healthcare sectors worldwide is expected to be overwhelmed not only to deal with individuals getting infected with the SARS-CoV-2 coronavirus and the short term symptoms or the severe cases, but more so with the so called ‘recovered’ and asymptomatic individuals as more reports are emerging that a variety of chronic medical and health conditions are arising and manifesting in such individuals.


 
One of the most common conditions that most COVID-19 ‘recovered’ and asymptomatic individuals are experiencing is fatigue or more correctly Myalgic Encephalomylitis or Chronic Fatigue Syndrome and in this case it is also referred to as Post Viral Fatigue Syndrome (PVFS). Studies are now showing that up to 70 percent of COVID-19 recovered and asymptomatic individuals are manifesting this condition. https://www.thailandmedical.news/news/post-covid-fatigue-irish-study-claims-44-70-percent-of-recovered-covid-19-patients-will-suffer-from-severe-fatigue-irrespective-of-disease-severity
 
The main symptom of post-viral fatigue is a significant lack of energy. One might also feel exhausted, even if one’ve been getting plenty of sleep and resting. Other symptoms that can accompany post-viral fatigue include:
concentration or memory problems, sore throat, headache, swollen lymph nodes and neuromuscular problems such as unexplained muscle or joint pain.
 
However it should be noted that at the moment that researchers are highlighting that that the fatigue conditions experienced by post COVID-19 patients might be different from the typical Myalgic Encephalomylitis or Chronic Fatigue Syndrome in terms or the cellular pathways that are triggering it. https://www.medrxiv.org/content/10.1101/2020.07.29.20164293v1
 
Even then, a key factor that seems to be associated with it is still inflammation and cellular metabolism.
 
Here, we at Thailand Medical News have assembled a list of supplements that could help with the Myalgic Encephalomylitis or Chronic Fatigue Syndrome especially in terms of Post Viral Fatigue Syndrome (PVFS). Though they are lots of supporting studies in terms of how these supplements can help, we have to point out that as of date there are no specific published studies that actually demonstrate that they work in the case of the COVID-19 ‘recovered’ patients and asymptomatic individuals although we have received positive feedback from various doctors and patients around the world. It should be noted that the COVID-19 disease only made its debut in January 2020 ad medical experts are only just discovering more facets about it day by day.

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We advise anyone attempting to take any of these supplements to treat themselves to first consult a licensed medical doctor to ensure they might not have any existing underlying medical conditions that can be aggravated by these supplements or if there are any drug interactions with any existing drugs that one might be already taking. Also do your own due diligence as some medical doctors are against any kind of supplements as they prefer prescribing toxic pharmaceuticals of which  they are making hefty commissions from them and also in some cases, some doctor are totally clueless about medical and scientific studies about these supplements and will simply brush it off.
 
It should be noted that chronic fatigue is a complex illness, and no one treatment plan works for everyone. Multi-faceted approaches are typically needed to help manage the syndrome's impactful symptoms, including incapacitating fatigue and pain.
 
1. Omega-3s and Omega-6s Essential Fatty Acids
 
Past research have shown that individuals with chronic fatigue syndrome have imbalanced levels of essential fatty acids (omega-3s and omega-6s), which may contribute to symptoms such as fatigue and body aches. https://pubmed.ncbi.nlm.nih.gov/30471769/
 
The human body needs to get essential fatty acids through nutrition because it cannot manufacture them on its own.
 
A few small studies have found that supplementing with a combination of essential fatty acids found in evening primrose oil and fish oil can lead to an improvement in symptoms. https://www.sciencedirect.com/science/article/pii/S0753332218342987?via%3Dihub and https://pubmed.ncbi.nlm.nih.gov/16380690/ and https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0404.1999.tb00667.x and https://www.researchgate.net/publication/8588398_Eicosapentaenoic_acid-rich_essential_fatty_acid_supplementation_in_chronic_fatigue_syndrome_associated_with_symptom_remission_and_structural_brain_changes
 
More studies are needed before essential fatty acids can be definitively recommended to ease symptoms of chronic fatigue syndrome, diets rich in essential fatty acids especially omega-3s have been shown to have many health benefits, including reducing inflammation and improving cardiovascular health. https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer/ and https://www.uscjournal.com/articles/omega-3-fatty-acids-science
 
Excellent dietary sources of omega-3s include fatty fish, like salmon, herring, and sardines, flaxseed, walnuts, chia, and certain oils.
 
2. Vitamin B12 and Folic Acid
 
Scientists have been exploring whether vitamin B12 injection or other means of supplementation, along with folic acid, can relieve CFS symptoms.
 
Interestingly, there is a biochemical theory as to how this may be of benefit: People with CFS show reduced methylation which plays a role in gene expression as well as regulation of many of the body's systems, including detoxification, cardiovascular and the neurologic system. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124648
 
Hence it is believed that Vitamin B12 and folic acid both promote healthy methylation pathways.
 
A research of B12 injections in addition to oral folic acid supplementation found that some subjects with CFS responded well, while others had only a mild response. A better response was associated with more frequent injections, lack of use of opioids, and a certain genetic phenotype. https://kyushu-u.pure.elsevier.com/en/publications/overview-of-medical-treatment-and-management-of-chronic-fatigue-s and