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BREAKING NEWS
Source: Coronavirus News  Nov 23, 2020  3 years, 4 months, 3 weeks, 3 days, 16 hours, 47 minutes ago

Coronavirus News: Could COVID-19 Create A Whole Generation Of ‘Virally-Castrated’ Eunuchs? Study Confirms Male Fertility Is At Risk!

Coronavirus News: Could COVID-19 Create A Whole Generation Of ‘Virally-Castrated’ Eunuchs? Study Confirms Male Fertility Is At Risk!
Source: Coronavirus News  Nov 23, 2020  3 years, 4 months, 3 weeks, 3 days, 16 hours, 47 minutes ago
Coronavirus News: A Turkish researcher, Dr Cemile Seymen from the Gazi University Institute of Health Sciences, Ankara-Turkey has warned based on his study findings that the COVID-91 disease is able to negatively affect male reproductive health and fertility.


 
The study findings were published in the peer reviewed journal of Medical Virology. https://onlinelibrary.wiley.com/doi/10.1002/jmv.26667
 
The COVID-19 outbreak has become a major pandemic threat worldwide. According to the existing clinical data, the SARS-CoV-2 coronavirus not only causes respiratory diseases and affects the lungs but also induces the histopathological or functional changes in various organs like the testis and also the male genital tract. The Renin‐Angiotensin System (RAS), also ACE 2 and TMPRSS2 play an important role in a cellular entry for SARS‐CoV‐2. Because of the male genital system presents high ACE 2 expression, the importance of this pathway increases in COVID‐19 cases. Due to the COVID‐19 pandemic affects the male genital system in direct or indirect ways and shows a negative impact on male reproduction, this new study focuses on the possible mechanisms underlying the damage caused by COVID‐19 to the testis and also other components of the male genital tract.
 
These findings are nothing new as Thailand Medical news was already warning on this development as early as February. https://www.thailandmedical.news/news/breaking-news!-latest-research-published-by-chinese-scientists-say-coronavirus-might-render-certain-male-patients-infertile
 
https://www.thailandmedical.news/news/breaking-male-infertility-research-shows-that-sars-cov-2-coronavirus-may-indirectly-cause-testicular-damage-in-male-covid-19-patients-and-also-orchiti
 
https://www.thailandmedical.news/news/sars-cov-2-news-ultrasound-diagnostic-imaging-shows-that-sars-cov-2-causes-acute-testicular-infection-in-a-high-proportion-of-male-covid-19-patients
 
The new research paper discusses the effects of the SARS-CoV-2 coronavirus may have on male fertility and summarizes study findings showing how the infection can negatively affect male reproductive health.
 
Dr Seymen says further studies are needed to investigate the roles that the host cell proteins angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) may play in infection since both of these proteins, which are involved in viral entry, are highly expressed in the male reproductive system.
 
To date very little data are available on the effects of COVID-19 on male fertility. Dr Seymen told Thailand Medical News, "There is a very limited number of data abo ut the effects of COVID-19 on male fertility, so it has become an important topic for researchers."
 
In order to gain viral entry, SARS-CoV-2 uses a surface structure called the spike protein to bind to the ACE2 receptor present on host cells.
 
A research published earlier this year showed that ACE2 messenger RNA was expressed in both germ and somatic cells of the testis. Other studies have found that ACE2 is expressed in spermatogonia, Leydig cells, and Sertoli cells.