COVID-19 Clinical Care: Kidney Failure Emerging As A Common Occurrence From COVID-19 Infections
Source: COVID-19 Clinical Care May 12, 2020 5 years, 10 months, 1 week, 4 days, 2 hours, 54 minutes ago
COVID-19 Clinical Care: According to a new research by Northwestern University, many COVID-19 patients are at risk for
acute kidney failure. Acute kidney failure also called
acute kidney injury (
AKI) is a serious complication of COVID-19 that's underreported and not well understood.
https://jasn.asnjournals.org/content/early/2020/05/04/ASN.2020040419
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The medical researchers said that the death rate for patients with severe acute kidney failure is about 50%.
Lead author Dr Daniel Batlle, a Professor of medicine and a kidney specialist at Northwestern, in Chicago told Thailand Medical News, "Patients in the hospital with COVID-19, and especially those in the ICU, are at risk for AKI, perhaps as many as 25% to 30%."
Dr Batlle and his colleagues reviewed two recent studies from China with details about kidney tissues from patients who died from COVID-19 for this new research study.
The Northwestern researchers said that the type of acute kidney failure in COVID-19 patients is complex and involves several factors not typically seen in an AKI patient in the intensive care unit (ICU).
Some of these significant factors include possible invasion of the kidneys by the coronavirus, a tendency to form blood clots, and the formation of active mediators of inflammation.
The study findings published in the
Journal of the American Society of Nephrology, is the first to examine possible mechanisms that cause acute kidney failure in COVID-19 patients, according to the authors.
Dr Batlle added, "These new findings should encourage health care providers to increase the focus on the kidneys and obtain proper information about kidney function and structure in COVID-19 patients who develop AKI."
He further added, "A better understanding of the mechanism will foster development of effective therapies beyond the supportive care in the ICU, which is already critically important as many of these patients require dialysis-related therapy."
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