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Source: Viral Persistence  Jun 06, 2021  2 years, 10 months, 2 weeks, 6 days, 54 minutes ago

COVID-19 News: WARNING! Millions Of Recovered COVID-19 Patients Could Be Walking Around With Residual Reservoirs Of The SARS-CoV-2 Virus In Them!

COVID-19 News: WARNING! Millions Of Recovered COVID-19 Patients Could Be Walking Around With Residual Reservoirs Of The SARS-CoV-2 Virus In Them!
Source: Viral Persistence  Jun 06, 2021  2 years, 10 months, 2 weeks, 6 days, 54 minutes ago
COVID-19 News: The COVID-19 pandemic can be best described as one of the worst managed pandemics in history and without proper leadership. The WHO or World Health Organization has been so incompetent in the handling of the SARS-CoV-2 breakout in China and they literally helped the spread of the Chinese virus throughout the world and yet none of their senior morons have been removed from positions nor any of them investigated for possible corruption or even disciplined. The stupid mainstream media are still continuing to interview these morons from time to time and even giving them lengthy coverage for whatever garbage spewing from their mouths.


 
To make things worse, the pandemic has all narratives and directions controlled by a group of greedy and unethical billionaires including numerous American tech billionaires and pharmaceutical giants together with the support of the US NIH, the US CDC and US FDA. It is hilarious that some stupid Americans were even hailing individuals like Dr Anthony Fauci, an Italian Jew as a sort of hero despite the numerous wrong advice he was dishing out in the beginning of the pandemic and his non-stop strategies to make President Trump look stupid. (PS: I am neither pro Trump or pro Biden, rather I am pro Truth with regards to the pandemic)
 
The way so called medical experts came up with protocols to test for the SARS-CoV-2 virus and also to assess that individuals have recovered from the COVID-19 disease is totally rubbish!
 
Testing a person after a period of 14 days or even when they are no longer exhibiting any symptoms by merely using a nasal swab PCR test is one of the most stupidest things ever! Even a saliva tests does not help.
 
It is shocking to see Western scientists and doctors merely using the protocols that were developed by the Chinese and till now are not questioning the reliability of these nasal swab tests.
 
Numerous studies have already shown that there are possibilities of viral persistence in recovered patients as the SARS-CoV-2 coronavirus is known to further itself into the gastrointestinal tracts and also other organs such as the liver, kidneys and even the brain!

https://www.thailandmedical.news/news/viral-persistence-georgia-state-university-study-indicates-that-sars-cov-2-may-hide-in-the-brain-and-cause-relapses-in-recovered-patients

https://www.thailandmedical.news/news/study-in-china-reveals-persistence-fecal-virus-shedding-in-children-deemed-recovered-from-covid-19-after-testing-negative-via-nasal-swab-tests

https://www.thailandmedical.news/news/covid-19-research-university-of-california-led-study-finds-that-brain-pericytes-could-be-entry-points-for-sars-cov-2-and-are-potential-reservoirs

 

https://www.thailandmedical.news/news/world-covid-19-news-global-deaths-crosses-1-6-million-milestone,-infections-pass-71-8-million-why-are-authorities-downplaying-viral-persistence

https://www.thailandmedical.news/news/children-s-hospital-los-angeles-led-study-alarmingly-shows-sars-cov-2-causing-viral-persistence-in-children-and-young-adults-with-cancer
 
https://www.thailandmedical.news/news/covid-19-news-yale-study-shockingly-finds-that-pbmc-myeloid-cells-harbors--sars-cov-2-genomes-with-implications-for-viral-persistence-and-misc-dangers
 
https://www.thailandmedical.news/news/study-claims-that-close-to-17-percent-of-recovered-covid-19-patients-still-carry-virus,-experts-disagree-as-current-test-cannot-detect-virus-in-intest
 
https://www.thailandmedical.news/news/covid-19-genomics-oxford-and-john-hopkins-study-shows-that-sars-cov-2-genome-possess-rna-secondary-structures-that-contributes-to-viral-persistence
 
https://www.thailandmedical.news/news/coronavirus-news-study-alarmingly-shows-that-3-percent-of-recovered-covid-19-patients-test-positive-for-live-and-infectious-sars-cov-2-virus
 
Studies have also shown that the SARS-CoV-2 is able to disrupt the human host immune system to accommodate its long term stay.

https://www.thailandmedical.news/news/coronavirus-warning-study-reveals-that-after-infection-phase,-the-sars-cov-2-manipulates-human-host-immune-system-to-facilitate-its-long-term-stay
 
The current nasal swab PCR test protocols are not able to indicate if a person has the presence of the SARS-Cov-2 coronavirus in other parts of the body including the gastrointestinal tract or even in other organs such as the liver, kidneys, brain or even the male testes. It cannot even pick up if a person has viremia ie the virus is present in the bloodstream.
 
A new study by researchers from Singapore further adds to the warning that millions of recovered COVID-19 patients globally could be walking around with residual reservoirs of the SARS-CoV-2 coronavirus in them!
 
The study team from Singapore had read with great interest the article published by Zuo et al, which highlighted the presence of SARS-CoV-2 RNA in stool samples during active and convalescence phases of COVID-19 infection. https://gut.bmj.com/content/70/2/276.abstract
 
To date however, no study has reported the presence of viral antigens within GI and hepatic organs during the convalescent phase.
 
Utilizing conventional immunohistochemistry, the study team detected SARS-CoV-2 nucleocapsid protein (NP) in the colon, appendix, ileum, haemorrhoid, liver, gallbladder and lymph nodes from five patients who recovered from COVID-19, ranging from 9 to 180 days after testing negative for SARS-CoV-2.
 
Notably, when multiple tissues were obtained from one patient, all the tissues showed the presence of the viral antigen, suggesting widespread multiorgan involvement of the viral infection. Interestingly, for the colon, the viral antigen was only present in normal colonic crypts and polyps but not in the neoplastic tissues.
 
Similar negative staining in the hepatocellular carcinoma tumour region was also observed albeit the positive staining in some of the scattered immune cells.
 
Validating their findings, the study team detected SARS-CoV-2 spike protein and RNA in the above-mentioned tissues using conventional immunohistochemistry and RNAscope, respectively.
 
Their study findings were published in the peer reviewed journal: GUT ( A BMJ or British Medical Journal publication.) https://gut.bmj.com/content/early/2021/06/01/gutjnl-2021-324280
 
Numerous groups have reported the phenomenon where patients who had recovered from mild or moderate COVID-19 later tested positive in nasopharyngeal swabs or sputum samples, raising concern for residual virus reservoirs and potential transmissibility in recovered individuals. https://www.nature.com/articles/s41598-020-68782-w
 
https://onlinelibrary.wiley.com/doi/full/10.1002/jmv.25905
 
Although respiratory transmission is responsible for most COVID-19 infections, there is increasing evidence of COVID-19 causing GI and hepatic manifestations, as studies reported the presence positive SARS-CoV-2 RNA in anal swabs and stool samples, despite nasopharyngeal or sputum specimens testing negative for the virus. https://www.gastrojournal.org/article/S0016-5085(20)30282-1/abstract
 
These study reports are in line with these new study findings of the intestinal tissues of patients with negative nasopharyngeal swab tests. Also, while SARS-CoV-2 viral antigen has been detected in the lung tissues of deceased patients despite negative nasopharyngeal swab tests, our findings constitute the first evidence of residual virus in extrapulmonary tissues during the convalescent phase, up to 6 months after recovery, in a non-postmortem setting. https://www.nature.com/articles/s41422-020-0318-5
 
It seems that a negative swab result might not necessarily indicate complete viral clearance from the body.
 
The study team stresses the need for further research in a larger cohort to explore the replication and infectivity of the virus in tissue specimens and to understand the GI and hepatic involvement in COVID-19.
 
Most importantly, newer test protocols should be developed to really ensure that individuals have truly recovered from the COVID-19 disease and are not having residual pockets of the virus in their bodies.
 
It should also be noted that viral persistence is not the only contributing factor to Long COVID. Numerous other factors could also be at play including viral proteins, disruption of various cellular pathways by the virus, prions released by the virus etc.
 
For more on Viral Persistence and the latest COVID-19 News, keep on logging to Thailand Medical News.
 
 
 
 

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