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COVID-19 Vaccine
COVID-19 Vaccine is a new segment dedicated to progress about about COVID-19 vaccines. Currently there is a lot of controversy and issues surrounding COVID-19 vaccines and this new segment will not only address these but also provides updates about COVID-19 vaccines developments and progress.
Source: COVID-19 Vaccine  Aug 04, 2020  16 hours ago
COVID-19 Vaccine: Russia’s Minister for Health Mikhail Murashko announced that Russia is planning a nationwide program to vaccinate its population against COVID-19 starting in October. The vaccine has not yet completed clinical trials. Murashko indicated they would begin by vaccinating teachers and health care workers.   He also told the RIA state news agency that while in t...
Source: COVID-19 Vaccines  Aug 03, 2020  2 days ago
COVID-19 Vaccines:  American researchers from ImmunityBio Inc. and Icahn School of Medicine at Mount Sinai in New York have developed a next generation COVID-19 vaccine: the bivalent human adenovirus serotype 5 (hAd5) vaccine for inducing both cellular and humoral immunity against the SARS-CoV-2 coronavirus, using both an S protein sequence optimized for cell surface expression...
Source: COVID-19 Vaccines  Jul 29, 2020  7 days ago
COVID-19 Vaccines: Research scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health report that two doses of an experimental vaccine to prevent coronavirus disease 2019 (COVID-19) induced robust immune responses and rapidly controlled the coronavirus in the upper and lower airways of rhesus macaques exposed to SARS-CoV-2.  ...
Source: COVID-19 Vaccine News  Jul 26, 2020  10 days ago
COVID-19 Vaccine News: Dynavax Technologies, a fully-integrated biopharmaceutical based in California has partnered with Taiwan-based Medigen Vaccine Biologics to develop a new adjuvanted Covid-19 vaccine candidate.   The new collaborative vaccine development will leverage on Medigen’s stable prefusion form of the SARS-CoV2 recombinant spike protein in combination with Dynavax&rs...
Source: COVID-19 Vaccine  Jul 23, 2020  13 days ago
COVID-19 Vaccine: California based Arcturus Therapeutics Holdings Inc., a clinical-stage messenger RNA medicines company focused on the discovery, development and commercialization of therapeutics for rare diseases and vaccines, and Duke-NUS Medical School, Singapore's flagship research-intensive graduate entry medical school, announced that the Clinical Trial Application for COVID-19 vaccine ...
Source: COVID-19 Vaccine Progress  Jul 22, 2020  14 days ago
COVID-19 Vaccine Progress: The Phase ½ clinical trial of BioNTech And Pfizer’s BNT162b1 RNA-Based Vaccine has demonstrated that the vaccine is able to elicit both T Cell And Neutralizing Antibodies Response.   The trial results were published by researchers from Germany and the United States on a preprint server and are yet to have been peer-reviewed. https://www.medrxiv.org/co...
Source: COVID-19 Vaccine Updates  Jul 21, 2020  15 days ago
COVID-19 Vaccine Updates: The clinical trial results of the Phase I/II trial of Oxford University and AstraZenaca’s ChAdOx1 nCoV-19 vaccine published in the scientific journal, The Lancet, indicate no early safety concerns and induces strong immune responses in both parts of the immune system. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31604-4/fulltext The ChA...
Source: COVID-19 Vaccine  Jul 21, 2020  15 days ago
COVID-19 Vaccine:  The phase 2 trial of China’s Ad5 vectored COVID-19 vaccine candidate that was conducted in Wuhan has found that the vaccine is safe and induces an immune response, according to trial findings published in The Lancet. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31605-6/fulltext#%20   The phase 2 randomized trial sought to evaluate the ...
Source: COVID-19 Vaccine  Jul 19, 2020  16 days ago
COVID-19 Vaccine:  It was announced that the First Phase-III clinical trial of Chinese state-owned pharmaceutical company Sinopharm's inactivated Covid-19 vaccine has started in Abu Dhabi. Head of Abu Dhabi’s health department becomes first volunteer for Covid-19 Phase III Chinese vaccine trials Interestingly the UAE health authorities recently issued a permit for up to 15,000 vo...
Source: COVID-19 Vaccine  Jul 17, 2020  19 days ago
COVID-19 Vaccine: Moderna has announced that said its COVID-19 vaccine candidate mRNA-1273 will advance to a 30,000-participant Phase III trial later this month, following publication of additional positive Phase I data from a study led by the NIH’s National Institute of Allergy and Infectious Diseases (NIAID). The “COVE” Phase III study (NCT04470427) is expected to begin regis...
Source: COVID-19 Vaccine  Jul 17, 2020  19 days ago
COVID-19 Vaccine Updates: Data from the Phase 1 trial of COVID-19 vaccine by AstraZeneca and Oxford University’s Jenner Institute is showing a robust defense against the novel coronavirus that has infected more than 13.6 million individuals across the globe   U.K. media yesterday began to report hints of data from the early-stage study of the vaccine candidate...
Source: COVID-19 Vaccine  Jul 15, 2020  21 days ago
COVID-19 Vaccine:  The Phase 1 trial of an investigational vaccine, mRNA-1273, designed to protect against SARS-CoV-2, the virus that causes COVID-19 disease, was generally well tolerated and prompted neutralizing antibody activity in healthy adults, according to US NIH authorities.   The interim results of the trial were published yesterday in The New England Journal of Medicine....
Source: COVID-19 Vaccine  Jul 15, 2020  21 days ago
COVID- 19 Vaccine: Canadian biophamaceutical company Medicago that is based in Quebec with branches in the U.S. announced that it has begun Phase I clinical trial for its plant-derived COVID-19 vaccine candidate. It has already administered the first doses of the candidate in healthy human subjects, and the company intends to initiate a Phase II/III trial this coming October.   Dr Nath...
Source: COVID-19 Vaccine  Jul 15, 2020  21 days ago
COVID-19 Vaccine: American researchers from Duke University-Durham have made an important discovery about the spike protein SARS-CoV-2 that could have a broad impact on vaccine studies.   The S or spike protein is the structure that binds to host cell angiotensin-converting enzyme 2 (ACE2) to enable viral attachment and entry during the infection process. The spike protein is also...
Source: COVID-19 Vaccine  Jul 14, 2020  22 days ago
COVID-19 Vaccine: There are more than 140 SARS-CoV-2 vaccines in development and the race for a successful candidate to help prevent COVID-19 is making many researchers jumpstart processes and in some cases even by pass safety protocols.   Although an effective and safe vaccine would be a major advance in the fight against COVID-19, there are challenges in evaluating the efficacy of&nb...
Source: COVID-19 Vaccine  Jul 13, 2020  22 days ago
COVID-19 Vaccine: Maryland based Altimmune, Inc., a clinical-stage biopharmaceutical company, has reported positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.   The research studies; a collaboration between the University of Alabama-Birmingham and Altimmune showed strong serum neutr...
Source: COVID-19 Vaccines  Jul 10, 2020  26 days ago
COVID-19 Vaccines: The U.S.National Institute of Allergy & Infectious Diseases (NIAID) has founded a new clinical trials network focused on enrolling volunteers in clinical trials for COVID-19 vaccines and monoclonal antibodies.   Various media have recently reported that sponsor companies are struggling to enroll patients in clinical trials for COVID-19 va...
Source: COVID-19 Vaccine Updates  Jul 08, 2020  28 days ago
COVID-19 Vaccine Updates: Maryland based Biotech company Novavax announced that it has been awarded US$1.6 billion toward late-stage clinical trials and large-scale manufacturing to produce 100 million doses of its COVID-19 vaccine starting this year through the Trump’s administration “Operation Warp Speed” program.   The new funding will enable Novavax  to complete la...
Source: COVID-19 Vaccine News  Jul 07, 2020  29 days ago
COVID-19 Vaccine News: Biotech manufacturing company-Emergent BioSolutions, based in Maryland, entered a five-year manufacturing services deal with Janssen Pharmaceutical, a Johnson & Johnson company, to manufacture J&J’s Ad26.COV2-S COVID-19 vaccine. Emergent will handle contract development and manufacturing (CDMO) services in a deal that is valued at ...
Source: COVID-19 Vaccine Updates  Jul 07, 2020  29 days ago
COVID-19 Vaccine Updates: It was announced that vaccine candidate COVAX-19 developed by Vaxine Pty Ltd and Flinders University will commence Phase 1 trials at the Royal Adelaide Hospital (RAH) to test its efficacy.   The phase I trial will provide initial safety and immune response data on 40 healthy participants aged between 18 and 65 years who have already been pre-screened.   Resear...
Source: COVID-19 Vaccine  Jul 06, 2020  30 days ago
COVID-19 Vaccine:  Professor of vaccinology at the University of Oxford, and one of the scientists leading the vaccine initiative, Dr Sarah Gilbert, told the U.K.'s Science and Technology Committee last week that their candidate vaccine has progressed to the phase III trial in the United Kingdom.   Phase III trials typically involves tens of thousands of research participants acros...
Source: COVID-19 Vaccine  Jul 05, 2020  1 month ago
COVID-19 Vaccine: Researchers from China have created an artificial protein that they say could be the basis of a vaccine to help ward off various deadly coronaviruses, including the pathogen that causes Covid-19 Copyright: Credit: Xinhua    The researchers from the Chinese CDC said the approach triggered a strong antibody response in mice and monkey trials to Middle Eas...
Source: COVID-19 Vaccine  Jul 04, 2020  1 month ago
COVID-19 Vaccine:  Indian pharmaceutical company, Zydus Cadila received the green signal from the Drug Controller General of India (DGCI) to start phase I and II of their clinical trials on human participants. Over 120 independent scientific bodies are in contention to find a potential COVID-19 vaccine. Over 7 vaccines are being researched in India and just this week, two candidate groups ...
Source: COVID-19 Vaccine Updates  Jul 04, 2020  1 month ago
COVID-19 Vaccine Updates:  Pharmaceutical and Biotech giants, Pfizer and BioNTech reported that the most advanced of four constructs of their messenger RNA (mRNA) vaccine candidate for COVID-19 showed encouraging immunogenicity and a favorable safety profile in preliminary Phase I/II data published in a preprint study. https://www.medrxiv.org/content/10.1101/2020.06.30.20142570v1   Bot...
Source: COVID-19 Vaccine  Jul 02, 2020  1 month ago
COVID-19 Vaccine:  Members of the National Institutes of Health's Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Vaccines Working Group assess practical considerations and prerequisites for using controlled human infection models (CHIMs), which can be used for human challenge studies, to support SARS-CoV-2 vaccine development.   In a new report published in th...

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