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Source: SARS-CoV-2 Variants  Jul 15, 2021  2 years, 9 months, 3 days, 6 hours, 24 minutes ago

Variant Warning: Scientist Urged To Pay Extra Surveillance To Emerging Third and Fourth Generation Variants Of the Delta, Gamma And Lambda Strains

Variant Warning: Scientist Urged To Pay Extra Surveillance To Emerging Third and Fourth Generation Variants Of the Delta, Gamma And Lambda Strains
Source: SARS-CoV-2 Variants  Jul 15, 2021  2 years, 9 months, 3 days, 6 hours, 24 minutes ago
Thailand Medical News is warning scientists, medical researches, genomic experts and virologist to pay careful attention to the second, third and fourth generation variants emerging from the Delta, Gamma and Lambda lineages.

Currently the world is too engrossed simply on the VOCs or variants of concern and also vaccines but very little is focused on the emerging second, third and fourth generation variants of the Delta, Gamma and Lambda strains as many are simply assuming that the mutations taking place on these new variants are too minute or subtle to have any impact.
 
In reality the chances of a completely new super Omega variant emerging is lesser compared to a super strain emerging from the Delta, Gamma or Lambda variants.
 
Though spotting minute mutations or deletions etc, it is these minute changes that are most like to be the major game changes in these ongoing pandemic.
 
The Delta variant currently has two second generation variants ie Delta Plus or the AY.1 and the newly debuted AY.2.
 
The Delta Plus variant, also known as B.1.617.2.1 is sometimes considered a “subvariant” of the Delta version. It has a mutation that allows the virus to better attack lung cells and potentially escape vaccines.
 
First identified in India, Delta Plus has now been found in the U.S., U.K., and nearly a dozen other countries. India has labeled it a variant of concern, but the U.S. CDC and WHO have not done so as it also reflects negatively on the their vaccines as being inefficient to curtail these variants.
 
Unknown to many the AY.2 variant made a debut in the last few weeks but some scientist are saying that both AY.1 and AY.2 are unlikely to be major game changers in the COVID-19 pandemic.
 
However a new AY.3 variant has been identified as a new Delta sub-lineage and it is defined by ORF1a: I3731V common AY.1 mutations except for S: K417.
 
The AY.3 is primarily seen in the US with single reclassified cases in UK and India.
 
Also Thailand Medical News has received information that a number of third generation variants have arisen from the AY.1, AY.2 and AY.3 spotting minute but totally newer mutations never seen before in other variants or strains so far.
 
Though these are very extremely small in sequencings, scientists from INSACOG, a consortium of government panel involved in genome sequencing of coronavirus who discovered these new third and fourth generation variants of the Delta virus are still in the midst of studying them and deciphering these new mutations.
 
As the vaccine program is initiated in many countries but at a slow pace together with the introduction of various antibody based therapeutics, it is e