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The exact cause of glioma is not clear, although some hereditary disorders are known to increase the likelihood of these tumors developing. Examples of these disorders include tuberous sclerosis and neurofibromatosis.
Gliomas are classified according to the specific type of cells involved, as follows:
Gliomas are also classified according to their grade. Low-grade gliomas are usually slow growing, non-malignant and are associated with a better outcome over high-grade gliomas, which are malignant and more aggressive.
Although no specific cause of glioma has been identified, research suggests that the following factors play a role: